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KMID : 0043320090320121705
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Archives of Pharmacal Research
2009 Volume.32 No. 12 p.1705 ~ p.1710
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Purunusides A-C, α-Glucosidase Inhibitory Homoisoflavone Glucosides from Prunus domestica
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Muhammad Iqbal Chouhdary
Shaheen Kosar
Itrat Fatima
Azhar Mahmood
Rehana Ahmed
Abdul Malik
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Abstract
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Purunusides A-C (1-3), new homoisoflavone glucosides together with the known compounds β-sitosterol (4) and 6,7-methylenedioxy-8-methoxycoumarin (5) have been isolated from nbutanol and ethyl acetate soluble fractions of Prunus domestica. Their structures were assigned on the basis of spectral studies. The compounds 1-3 showed potent inhibitory activity against the enzyme α-glucosidase.
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KEYWORD
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Prunus domestica, Rosaceae, Purunusides A-C, α-Glucosidase inhibition
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